Dangerous Depo Deception Continues

While Admitting Risks, WHO Continues to Recommend
 Injectable Contraceptives for Women at High Risk of Contracting HIV

by Jonathan Abbamonte
Population Research Institute

Since 1991, numerous studies have shown that injectable contraceptives like Depo-Provera may increase women’s risk of contracting HIV. The World Health Organization (WHO) has now changed its recommendations on certain injectable contraceptives in light of mounting evidence and increasing concern.

A new guidance statement recently released by the WHO has moved progestogen-only injectable contraceptives from category 1 to category 2 for women at high risk of contracting HIV.

A meta-analytical study[1] sponsored by the Population Research Institute released last year found that women using certain injectable contraceptives (DMPA-IM) were nearly fifty percent more likely to contract HIV (HR: 1.49, 95% CI 1.28 – 1.73). Other meta-analytical studies using different methods have arrived at similar results.[2]-[3]

Many recent studies have also explored possible biological explanations for why medroxyprogesterone acetate (MPA), the active ingredient in injectable contraceptive like Depo-Provera, may increase the risk for HIV transmission or viral replication.

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